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ATF1-CREB-1 translocation by RT PCR
The ATF1-CREB-1 translocation by RT PCR test is performed to detect a specific gene fusion involving the ATF1 gene on chromosome 12 and the CREB1 gene on chromosome 2, which results from a chromosomal translocation. This fusion is commonly associated with cert...
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The ATF1-CREB-1 translocation by RT PCR test is performed to detect a specific gene fusion involving the ATF1 gene on chromosome 12 and the CREB1 gene on chromosome 2, which results from a chromosomal translocation. This fusion is commonly associated...
Understanding ATF1-CREB-1 translocation by RT PCR
The ATF1-CREB-1 translocation by RT PCR test is performed to detect a specific gene fusion involving the ATF1 gene on chromosome 12 and the CREB1 gene on chromosome 2, which results from a chromosomal translocation. This fusion is commonly associated with certain rare tumors, such as clear cell sarcoma and angiofibroma of soft tissue. In this test, RNA is extracted and converted into cDNA, and the quality of the sample is confirmed using a housekeeping gene assay (PGK assay). A successful amplification in this step...
What does ATF1-CREB-1 translocation by RT PCR measure?
The ATF1-CREB-1 translocation by RT PCR test is performed to detect a specific gene fusion involving the ATF1 gene on chromosome 12 and the CREB1 gene on chromosome 2, which results from a chromosomal translocation. This fusion is commonly associated with certain rare tumors, such as clear cell sarcoma and angiofibroma of soft tissue. In this test, RNA is extracted and converted into cDNA, and the quality of the sample is confirmed using a housekeeping gene assay (PGK assay). A successful amplification in this step...
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