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EWS-FLI-1 translocation by RT PCR

The EWS-FLI-1 translocation by RT PCR test is a genetic test used to help diagnose Ewing sarcoma, a rare type of bone or soft tissue cancer that mainly affects children and young adults. Ewing sarcoma is commonly caused by a genetic change where parts of two d...

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The EWS-FLI-1 translocation by RT PCR test is a genetic test used to help diagnose Ewing sarcoma, a rare type of bone or soft tissue cancer that mainly affects children and young adults. Ewing sarcoma is commonly caused by a genetic change where part...

Understanding EWS-FLI-1 translocation by RT PCR

The EWS-FLI-1 translocation by RT PCR test is a genetic test used to help diagnose Ewing sarcoma, a rare type of bone or soft tissue cancer that mainly affects children and young adults. Ewing sarcoma is commonly caused by a genetic change where parts of two different chromosomes (chromosome 11 and chromosome 22) swap places. This creates an abnormal fusion gene called EWSR1::FLI1. During the test, genetic material (RNA) is extracted from the tissue and converted into cDNA. The quality of the sample is first checke...

What does EWS-FLI-1 translocation by RT PCR measure?

The EWS-FLI-1 translocation by RT PCR test is a genetic test used to help diagnose Ewing sarcoma, a rare type of bone or soft tissue cancer that mainly affects children and young adults. Ewing sarcoma is commonly caused by a genetic change where parts of two different chromosomes (chromosome 11 and chromosome 22) swap places. This creates an abnormal fusion gene called EWSR1::FLI1. During the test, genetic material (RNA) is extracted from the tissue and converted into cDNA. The quality of the sample is first checke...

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