Liver Kidney Microsomal (LKM) Antibody, IFA

Understanding Liver Kidney Microsomal (LKM) Antibody, IFA

Autoimmune hepatitis (AIH) is a chronic liver disease in which the body's immune system mistakenly attacks the liver, causing inflammation and damage. There are two main types of AIH: Type 1, which is the most common and can affect people of any age, and Type 2, which primarily affects children and young adults with a higher occurrence in females. LKM-1 antibodies are autoantibodies that target specific liver and kidney cell structures. These antibodies are particular for autoimmune hepatitis type 2 (AIH-2), and th...

What does Liver Kidney Microsomal (LKM) Antibody, IFA measure?

The Liver Kidney Microsomal (LKM) Antibody, IFA or LKM-1 antibody test is a blood test used to detect the presence of antibodies directed against liver and kidney microsomal antigens (produced in various liver conditions). This test helps diagnose autoimmune liver diseases, particularly type 2 autoimmune hepatitis (AIH-2), distinguishing it from other liver conditions such as type 1 autoimmune hepatitis (AIH-1), viral hepatitis, drug-induced liver injury, and other liver disorders.