Extractable Nuclear Antigens (ENA) Profile, Quantitative
168 hours
₹10,500View detailsScl-70 Antibody
The Scl-70 Antibody test detects antibodies against topoisomerase I (SCL-70) in the blood. This test supports evaluation and differentiation of systemic sclerosis (scleroderma) from other connective tissue disorders.
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The Scl-70 Antibody test detects antibodies against topoisomerase I (SCL-70) in the blood. This test supports evaluation and differentiation of systemic sclerosis (scleroderma) from other connective tissue disorders.
Understanding Scl-70 Antibody
SCL-70, also known as DNA topoisomerase I, is an enzyme found in the cell nucleus that helps unwind DNA during replication and transcription. In certain autoimmune conditions, the immune system mistakenly produces antibodies against this enzyme. The presence of SCL-70 antibodies in the blood suggests abnormal immune activity and is considered a significant marker for systemic sclerosis (scleroderma).
SCL-70 antibodies are strongly associated with diffuse cutaneous systemic sclerosis, a severe form of scleroderma t...
What does Scl-70 Antibody measure?
The Scl-70 Antibody test detects antibodies against topoisomerase I (SCL-70) in the blood. This test supports evaluation and differentiation of systemic sclerosis (scleroderma) from other connective tissue disorders.
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