Tissue Transglutaminase Antibody, IgA

Understanding Tissue Transglutaminase Antibody, IgA

Tissue transglutaminase (tTG) is an enzyme that plays an important role in various biological processes. One of its key functions is to help in the formation of stable protein structures by catalyzing the binding of proteins. tTG enzyme is implicated in the immune response triggered by gluten (a protein found in cereals like wheat, barley, and rye and foods like cakes, bread, and pasta) consumption.

In individuals with celiac disease, exposure to gluten often prompts an abnormal immune response where antibodies, i...

What does Tissue Transglutaminase Antibody, IgA measure?

A Tissue Transglutaminase Antibody, IgA test helps to identify the presence of specific antibodies in the blood associated with celiac disease, an autoimmune disorder triggered by the ingestion of gluten-containing foods. It helps assess the immune response to gluten, helping in the assessment and management of celiac disease.