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TP53 Sequencing
Mutations in TP53 gene are associated with the deletion of chromosome 17. This is indicative of poor prognosis in Multiple Myeloma (MM) cases. Early cases of MM may not show this deletion but as the disease advances, 17p deletion can be detected. Screening for...
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Mutations in TP53 gene are associated with the deletion of chromosome 17. This is indicative of poor prognosis in Multiple Myeloma (MM) cases. Early cases of MM may not show this deletion but as the disease advances, 17p deletion can be detected. Scr...
Understanding TP53 Sequencing
Mutations in TP53 gene are associated with the deletion of chromosome 17. This is indicative of poor prognosis in Multiple Myeloma (MM) cases. Early cases of MM may not show this deletion but as the disease advances, 17p deletion can be detected. Screening for 17p deletion in MM cases aids management decisions & directs these high-risk patients toward alternative therapies. This deletion has also been detected in Chronic Lymphocytic Leukemia (CLL) & is associated with poor prognosis.
What does TP53 Sequencing measure?
Mutations in TP53 gene are associated with the deletion of chromosome 17. This is indicative of poor prognosis in Multiple Myeloma (MM) cases. Early cases of MM may not show this deletion but as the disease advances, 17p deletion can be detected. Screening for 17p deletion in MM cases aids management decisions & directs these high-risk patients toward alternative therapies. This deletion has also been detected in Chronic Lymphocytic Leukemia (CLL) & is associated with poor prognosis.
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